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Human Cancer Cells Signal Their Competitive Fitness Through MYC Activity

MYC-mediated cell competition is a cell-cell interaction mechanism known to play an evolutionary role during development from Drosophila to mammals. Cells expressing low levels of MYC, called losers, are committed to die by nearby cells with high MYC activity, called winners, that overproliferate to...

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Detalles Bibliográficos
Autores principales: Di Giacomo, Simone, Sollazzo, Manuela, de Biase, Dario, Ragazzi, Moira, Bellosta, Paola, Pession, Annalisa, Grifoni, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626713/
https://www.ncbi.nlm.nih.gov/pubmed/28974715
http://dx.doi.org/10.1038/s41598-017-13002-1