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Loss of Endometrial Sodium Glucose Cotransporter SGLT1 is Detrimental to Embryo Survival and Fetal Growth in Pregnancy
Embryo implantation requires a hospitable uterine environment. A key metabolic change that occurs during the peri-implantation period, and throughout early pregnancy, is the rise in endometrial glycogen content. Glycogen accumulation requires prior cellular uptake of glucose. Here we show that both...
Autores principales: | Salker, Madhuri S., Singh, Yogesh, Zeng, Ni, Chen, Hong, Zhang, Shaqiu, Umbach, Anja T, Fakhri, Hajar, Kohlhofer, Ursula, Quintanilla-Martinez, Leticia, Durairaj, Ruban R. Peter, Barros, Flavio S. V., Vrljicak, Pavle, Ott, Sascha, Brucker, Sara Y, Wallwiener, Diethelm, Vrhovac Madunić, Ivana, Breljak, Davorka, Sabolić, Ivan, Koepsell, Hermann, Brosens, Jan J., Lang, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626729/ https://www.ncbi.nlm.nih.gov/pubmed/28974690 http://dx.doi.org/10.1038/s41598-017-11674-3 |
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