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Human intestinal organoids express histo-blood group antigens, bind norovirus VLPs, and support limited norovirus replication

Through pluripotent stem cell (PSC) technology, human intestinal organoids (HIOs) with remarkably similarity to the fetal intestine in cellular composition, architecture, and absorptive/secretory functions have been successfully developed, providing a useful in vitro model system to study the struct...

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Detalles Bibliográficos
Autores principales: Zhang, Dongsheng, Tan, Ming, Zhong, Weiming, Xia, Ming, Huang, Pengwei, Jiang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626734/
https://www.ncbi.nlm.nih.gov/pubmed/28974702
http://dx.doi.org/10.1038/s41598-017-12736-2