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Human intestinal organoids express histo-blood group antigens, bind norovirus VLPs, and support limited norovirus replication
Through pluripotent stem cell (PSC) technology, human intestinal organoids (HIOs) with remarkably similarity to the fetal intestine in cellular composition, architecture, and absorptive/secretory functions have been successfully developed, providing a useful in vitro model system to study the struct...
Autores principales: | Zhang, Dongsheng, Tan, Ming, Zhong, Weiming, Xia, Ming, Huang, Pengwei, Jiang, Xi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626734/ https://www.ncbi.nlm.nih.gov/pubmed/28974702 http://dx.doi.org/10.1038/s41598-017-12736-2 |
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