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Time-lapse imaging of microRNA activity reveals the kinetics of microRNA activation in single living cells

MicroRNAs (miRNAs) are small, non-coding RNAs that play critical roles in the post-transcriptional regulation of gene expression. Although the molecular mechanisms of the biogenesis and activation of miRNA have been extensively studied, the details of their kinetics within individual living cells re...

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Detalles Bibliográficos
Autores principales: Ando, Hideaki, Hirose, Matsumi, Kurosawa, Gen, Impey, Soren, Mikoshiba, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626736/
https://www.ncbi.nlm.nih.gov/pubmed/28974737
http://dx.doi.org/10.1038/s41598-017-12879-2