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Addressing the role of the α-helical extension in the folding of the third PDZ domain from PSD-95
PDZ domains are one of the most important protein-protein interaction domains in human. While presenting a conserved three dimensional structure, a substantial number of PDZ domains display structural extensions suggested to be involved in their folding and binding mechanisms. The C-terminal α-helix...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626748/ https://www.ncbi.nlm.nih.gov/pubmed/28974728 http://dx.doi.org/10.1038/s41598-017-12827-0 |