High-density microprojection array delivery to rat skin of low doses of trivalent inactivated poliovirus vaccine elicits potent neutralising antibody responses

To secure a polio-free world, the live attenuated oral poliovirus vaccine (OPV) will eventually need to be replaced with inactivated poliovirus vaccines (IPV). However, current IPV delivery is less suitable for campaign use than OPV, and more expensive. We are progressing a microarray patch delivery...

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Detalles Bibliográficos
Autores principales: Muller, David A., Fernando, Germain J. P., Owens, Nick S., Agyei-Yeboah, Christiana, Wei, Jonathan C. J., Depelsenaire, Alexandra C. I., Forster, Angus, Fahey, Paul, Weldon, William C., Oberste, M. Steven, Young, Paul R., Kendall, Mark A. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626768/
https://www.ncbi.nlm.nih.gov/pubmed/28974777
http://dx.doi.org/10.1038/s41598-017-13011-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626768/
https://www.ncbi.nlm.nih.gov/pubmed/28974777
http://dx.doi.org/10.1038/s41598-017-13011-0

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