Targeting the alternative sigma factor RpoN to combat virulence in Pseudomonas aeruginosa

Pseudomonas aeruginosa is a Gram-negative, opportunistic pathogen that infects immunocompromised and cystic fibrosis patients. Treatment is difficult due to antibiotic resistance, and new antimicrobials are needed to treat infections. The alternative sigma factor 54 (σ(54), RpoN), regulates many vir...

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Detalles Bibliográficos
Autores principales: Lloyd, Megan G., Lundgren, Benjamin R., Hall, Clayton W., Gagnon, Luke B.-P., Mah, Thien-Fah, Moffat, Jennifer F., Nomura, Christopher T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626770/
https://www.ncbi.nlm.nih.gov/pubmed/28974743
http://dx.doi.org/10.1038/s41598-017-12667-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626770/
https://www.ncbi.nlm.nih.gov/pubmed/28974743
http://dx.doi.org/10.1038/s41598-017-12667-y

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