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Acinar cells in the neonatal pancreas grow by self-duplication and not by neogenesis from duct cells

Pancreatic acinar cells secrete digestive enzymes necessary for nutrient digestion in the intestine. They are considered the initiating cell type of pancreatic cancer and are endowed with differentiation plasticity that has been harnessed to regenerate endocrine beta cells. However, there is still u...

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Detalles Bibliográficos
Autores principales: Houbracken, Isabelle, Bouwens, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626771/
https://www.ncbi.nlm.nih.gov/pubmed/28974717
http://dx.doi.org/10.1038/s41598-017-12721-9