A Potent Tartrate Resistant Acid Phosphatase Inhibitor to Study the Function of TRAP in Alveolar Macrophages

The enzyme tartrate resistant acid phosphatase (TRAP, two isoforms 5a and 5b) is highly expressed in alveolar macrophages, but its function there is unclear and potent selective inhibitors of TRAP are required to assess functional aspects of the protein. We found higher TRAP activity/expression in l...

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Detalles Bibliográficos
Autores principales: Boorsma, Carian E., van der Veen, T. Anienke, Putri, Kurnia S. S., de Almeida, Andreia, Draijer, Christina, Mauad, Thais, Fejer, Gyorgy, Brandsma, Corry-Anke, van den Berge, Maarten, Bossé, Yohan, Sin, Don, Hao, Ke, Reithmeier, Anja, Andersson, Göran, Olinga, Peter, Timens, Wim, Casini, Angela, Melgert, Barbro N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626781/
https://www.ncbi.nlm.nih.gov/pubmed/28974738
http://dx.doi.org/10.1038/s41598-017-12623-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626781/
https://www.ncbi.nlm.nih.gov/pubmed/28974738
http://dx.doi.org/10.1038/s41598-017-12623-w

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