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Chondroitin Sulfate Is Required for Onset and Offset of Critical Period Plasticity in Visual Cortex

Ocular dominance plasticity is easily observed during the critical period in early postnatal life. Chondroitin sulfate (CS) is the most abundant component in extracellular structures called perineuronal nets (PNNs), which surround parvalbumin-expressing interneurons (PV-cells). CS accumulates in PNN...

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Detalles Bibliográficos
Autores principales: Hou, Xubin, Yoshioka, Nozomu, Tsukano, Hiroaki, Sakai, Akiko, Miyata, Shinji, Watanabe, Yumi, Yanagawa, Yuchio, Sakimura, Kenji, Takeuchi, Kosei, Kitagawa, Hiroshi, Hensch, Takao K., Shibuki, Katsuei, Igarashi, Michihiro, Sugiyama, Sayaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626782/
https://www.ncbi.nlm.nih.gov/pubmed/28974755
http://dx.doi.org/10.1038/s41598-017-04007-x