The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration

Schwann cell dedifferentiation from a myelinating to a progenitor-like cell underlies the remarkable ability of peripheral nerves to regenerate following injury. However, the molecular identity of the differentiated and dedifferentiated states in vivo has been elusive. Here, we profiled Schwann cell...

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Detalles Bibliográficos
Autores principales: Clements, Melanie P., Byrne, Elizabeth, Camarillo Guerrero, Luis F., Cattin, Anne-Laure, Zakka, Leila, Ashraf, Azhaar, Burden, Jemima J., Khadayate, Sanjay, Lloyd, Alison C., Marguerat, Samuel, Parrinello, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626803/
https://www.ncbi.nlm.nih.gov/pubmed/28957681
http://dx.doi.org/10.1016/j.neuron.2017.09.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626803/
https://www.ncbi.nlm.nih.gov/pubmed/28957681
http://dx.doi.org/10.1016/j.neuron.2017.09.008

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