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Synaptic Transmission Optimization Predicts Expression Loci of Long-Term Plasticity

Long-term modifications of neuronal connections are critical for reliable memory storage in the brain. However, their locus of expression—pre- or postsynaptic—is highly variable. Here we introduce a theoretical framework in which long-term plasticity performs an optimization of the postsynaptic resp...

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Detalles Bibliográficos
Autores principales: Costa, Rui Ponte, Padamsey, Zahid, D’Amour, James A., Emptage, Nigel J., Froemke, Robert C., Vogels, Tim P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626823/
https://www.ncbi.nlm.nih.gov/pubmed/28957667
http://dx.doi.org/10.1016/j.neuron.2017.09.021