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Synaptic Transmission Optimization Predicts Expression Loci of Long-Term Plasticity
Long-term modifications of neuronal connections are critical for reliable memory storage in the brain. However, their locus of expression—pre- or postsynaptic—is highly variable. Here we introduce a theoretical framework in which long-term plasticity performs an optimization of the postsynaptic resp...
Autores principales: | Costa, Rui Ponte, Padamsey, Zahid, D’Amour, James A., Emptage, Nigel J., Froemke, Robert C., Vogels, Tim P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626823/ https://www.ncbi.nlm.nih.gov/pubmed/28957667 http://dx.doi.org/10.1016/j.neuron.2017.09.021 |
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