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One-Step Fabrication of Bone Morphogenetic Protein-2 Gene-Activated Porous Poly-L-Lactide Scaffold for Bone Induction

Bone morphogenetic protein 2 (BMP2) is an efficacious inducer for the osteogenesis of mesenchymal stem cells (MSCs). Conventional applications of BMP2 have involved either the direct incorporation of BMP2 protein or ex vivo BMP2 gene transfer into stem cells prior to their transplantation. These app...

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Detalles Bibliográficos
Autores principales: Xue, Jingwen, Lin, Hang, Bean, Allison, Tang, Ying, Tan, Jian, Tuan, Rocky S., Wang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626914/
https://www.ncbi.nlm.nih.gov/pubmed/29018836
http://dx.doi.org/10.1016/j.omtm.2017.08.008