Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins

The Gram-negative bacterial cell wall component lipopolysaccharide (LPS) is recognized by the noncanonical inflammasome protein caspase-11 in the cytosol of infected host cells and thereby prompts an inflammatory immune response linked to sepsis. Host guanylate binding proteins (GBPs) promote infect...

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Detalles Bibliográficos
Autores principales: Finethy, Ryan, Luoma, Sarah, Orench-Rivera, Nichole, Feeley, Eric M., Haldar, Arun K., Yamamoto, Masahiro, Kanneganti, Thirumala-Devi, Kuehn, Meta J., Coers, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626967/
https://www.ncbi.nlm.nih.gov/pubmed/28974614
http://dx.doi.org/10.1128/mBio.01188-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626967/
https://www.ncbi.nlm.nih.gov/pubmed/28974614
http://dx.doi.org/10.1128/mBio.01188-17

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