Cargando…
Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins
The Gram-negative bacterial cell wall component lipopolysaccharide (LPS) is recognized by the noncanonical inflammasome protein caspase-11 in the cytosol of infected host cells and thereby prompts an inflammatory immune response linked to sepsis. Host guanylate binding proteins (GBPs) promote infect...
Autores principales: | Finethy, Ryan, Luoma, Sarah, Orench-Rivera, Nichole, Feeley, Eric M., Haldar, Arun K., Yamamoto, Masahiro, Kanneganti, Thirumala-Devi, Kuehn, Meta J., Coers, Jörn |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626967/ https://www.ncbi.nlm.nih.gov/pubmed/28974614 http://dx.doi.org/10.1128/mBio.01188-17 |
Ejemplares similares
-
Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity
por: Orench-Rivera, Nichole, et al.
Publicado: (2021) -
Genome-Wide Assessment of Outer Membrane Vesicle Production in Escherichia coli
por: Kulp, Adam J., et al.
Publicado: (2015) -
Guanylate Binding Proteins Restrict Leishmania donovani Growth in Nonphagocytic Cells Independent of Parasitophorous Vacuolar Targeting
por: Haldar, Arun Kumar, et al.
Publicado: (2020) -
The transcription factor IRF1 and guanylate-binding proteins target AIM2 inflammasome activation by Francisella infection
por: Man, Si Ming, et al.
Publicado: (2015) -
Guanylate binding proteins facilitate caspase-11-dependent pyroptosis in response to type 3 secretion system-negative Pseudomonas aeruginosa
por: Balakrishnan, Arjun, et al.
Publicado: (2018)