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Characterization and Exploitation of CRISPR Loci in Bifidobacterium longum

Diverse CRISPR-Cas systems provide adaptive immunity in many bacteria and most archaea, via a DNA-encoded, RNA-mediated, nucleic-acid targeting mechanism. Over time, CRISPR loci expand via iterative uptake of invasive DNA sequences into the CRISPR array during the adaptation process. These genetic v...

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Detalles Bibliográficos
Autores principales: Hidalgo-Cantabrana, Claudio, Crawley, Alexandra B., Sanchez, Borja, Barrangou, Rodolphe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626976/
https://www.ncbi.nlm.nih.gov/pubmed/29033911
http://dx.doi.org/10.3389/fmicb.2017.01851