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Characterization and Exploitation of CRISPR Loci in Bifidobacterium longum

Diverse CRISPR-Cas systems provide adaptive immunity in many bacteria and most archaea, via a DNA-encoded, RNA-mediated, nucleic-acid targeting mechanism. Over time, CRISPR loci expand via iterative uptake of invasive DNA sequences into the CRISPR array during the adaptation process. These genetic v...

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Detalles Bibliográficos
Autores principales:	Hidalgo-Cantabrana, Claudio, Crawley, Alexandra B., Sanchez, Borja, Barrangou, Rodolphe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626976/ https://www.ncbi.nlm.nih.gov/pubmed/29033911 http://dx.doi.org/10.3389/fmicb.2017.01851

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