Cyclotides Isolated from an Ipecac Root Extract Antagonize the Corticotropin Releasing Factor Type 1 Receptor

Cyclotides are plant derived, cystine-knot stabilized peptides characterized by their natural abundance, sequence variability and structural plasticity. They are abundantly expressed in Rubiaceae, Psychotrieae in particular. Previously the cyclotide kalata B7 was identified to modulate the human oxy...

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Detalles Bibliográficos
Autores principales: Fahradpour, Mohsen, Keov, Peter, Tognola, Carlotta, Perez-Santamarina, Estela, McCormick, Peter J., Ghassempour, Alireza, Gruber, Christian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627009/
https://www.ncbi.nlm.nih.gov/pubmed/29033832
http://dx.doi.org/10.3389/fphar.2017.00616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627009/
https://www.ncbi.nlm.nih.gov/pubmed/29033832
http://dx.doi.org/10.3389/fphar.2017.00616

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