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Cyclotides Isolated from an Ipecac Root Extract Antagonize the Corticotropin Releasing Factor Type 1 Receptor
Cyclotides are plant derived, cystine-knot stabilized peptides characterized by their natural abundance, sequence variability and structural plasticity. They are abundantly expressed in Rubiaceae, Psychotrieae in particular. Previously the cyclotide kalata B7 was identified to modulate the human oxy...
Autores principales: | Fahradpour, Mohsen, Keov, Peter, Tognola, Carlotta, Perez-Santamarina, Estela, McCormick, Peter J., Ghassempour, Alireza, Gruber, Christian W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627009/ https://www.ncbi.nlm.nih.gov/pubmed/29033832 http://dx.doi.org/10.3389/fphar.2017.00616 |
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