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Interactions of the Bacillus subtilis DnaE polymerase with replisomal proteins modulate its activity and fidelity

During Bacillus subtilis replication two replicative polymerases function at the replisome to collectively carry out genome replication. In a reconstituted in vitro replication assay, PolC is the main polymerase while the lagging strand DnaE polymerase briefly extends RNA primers synthesized by the...

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Detalles Bibliográficos
Autores principales: Paschalis, Vasileios, Le Chatelier, Emmanuelle, Green, Matthew, Képès, François, Soultanas, Panos, Janniere, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627055/
https://www.ncbi.nlm.nih.gov/pubmed/28878042
http://dx.doi.org/10.1098/rsob.170146