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Mechanistic insights into molecular evolution of species-specific differential glycosaminoglycan binding surfaces in growth-related oncogene chemokines

Chemokines are chemotactic cytokines involved in leucocyte trafficking to infected tissue. Growth-related oncogene (GRO) chemokines namely CXCL1, CXCL2 and CXCL3 are neutrophil activating chemokines sharing a conserved three-dimensional structure, but encompassing functional diversity due to gene du...

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Detalles Bibliográficos
Autores principales: Gulati, Khushboo, Jamsandekar, Minal, Poluri, Krishna Mohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627130/
https://www.ncbi.nlm.nih.gov/pubmed/28989790
http://dx.doi.org/10.1098/rsos.171059