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Sweepstake evolution revealed by population-genetic analysis of copy-number alterations in single genomes of breast cancer

Single-cell sequencing is a promising technology that can address cancer cell evolution by identifying genetic alterations in individual cells. In a recent study, genome-wide DNA copy numbers of single cells were accurately quantified by single-cell sequencing in breast cancers. Phylogenetic-tree an...

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Detalles Bibliográficos
Autores principales: Kato, Mamoru, Vasco, Daniel A., Sugino, Ryuichi, Narushima, Daichi, Krasnitz, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627131/
https://www.ncbi.nlm.nih.gov/pubmed/28989791
http://dx.doi.org/10.1098/rsos.171060