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Polycomb complexes in X chromosome inactivation

Identifying the critical RNA binding proteins (RBPs) that elicit Xist mediated silencing has been a key goal in X inactivation research. Early studies implicated the Polycomb proteins, a family of factors linked to one of two major multiprotein complexes, PRC1 and PRC2 (Wang 2001 Nat. Genet. 28, 371...

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Detalles Bibliográficos
Autor principal: Brockdorff, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627167/
https://www.ncbi.nlm.nih.gov/pubmed/28947664
http://dx.doi.org/10.1098/rstb.2017.0021