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Sulforaphane exerts anti-angiogenesis effects against hepatocellular carcinoma through inhibition of STAT3/HIF-1α/VEGF signalling

Angiogenesis plays an important role in hepatocellular carcinoma (HCC), the inhibition of which is explored for cancer prevention and treatment. The dietary phytochemical sulforaphane (SFN) is known for its anti-cancer properties in vitro and in vivo; but until now, no study has focused on the role...

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Detalles Bibliográficos
Autores principales: Liu, Peng, Atkinson, Samuel J., Akbareian, Sophia E., Zhou, Zhigang, Munsterberg, Andrea, Robinson, Stephen D., Bao, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627255/
https://www.ncbi.nlm.nih.gov/pubmed/28978924
http://dx.doi.org/10.1038/s41598-017-12855-w