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Global misregulation of genes largely uncoupled to DNA methylome epimutations characterizes a congenital overgrowth syndrome

Assisted reproductive therapies (ART) have become increasingly common worldwide and numerous retrospective studies have indicated that ART-conceived children are more likely to develop the overgrowth syndrome Beckwith-Wiedemann (BWS). In bovine, the use of ART can induce a similar overgrowth conditi...

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Detalles Bibliográficos
Autores principales: Chen, Zhiyuan, Hagen, Darren E., Ji, Tieming, Elsik, Christine G., Rivera, Rocío M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627257/
https://www.ncbi.nlm.nih.gov/pubmed/28978943
http://dx.doi.org/10.1038/s41598-017-13012-z