Alpha-D-glucan nanoparticulate adjuvant induces a transient inflammatory response at the injection site and targets antigen to migratory dendritic cells

Biodegradable nanoparticles with functionalized surfaces are attractive candidates as vaccine adjuvants. Nano-11 are cationic dendrimer-like α-D-glucan nanoparticles with a diameter of 70–80 nm. Mice injected with antigen formulated with Nano-11 developed antibody titers that were similar or greater...

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Detalles Bibliográficos
Autores principales: Lu, Fangjia, Mosley, Yung-Yi C., Rodriguez Rosales, Randol J., Carmichael, Brooke E., Elesela, Srikanth, Yao, Yuan, HogenEsch, Harm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627279/
https://www.ncbi.nlm.nih.gov/pubmed/29263865
http://dx.doi.org/10.1038/s41541-017-0007-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627279/
https://www.ncbi.nlm.nih.gov/pubmed/29263865
http://dx.doi.org/10.1038/s41541-017-0007-7

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