10-Hydroxy-2-decenoic acid, a natural product, improves hyperglycemia and insulin resistance in obese/diabetic KK-Ay mice, but does not prevent obesity

10-Hydroxy-2-decenoic acid (10H2DA) is a fatty acid found in royal jelly (RJ). In healthy mice, it activates 5’-AMP-activated protein kinase (AMPK) and increases glucose transporter 4 (GLUT4) translocation. Therefore, we examined whether 10H2DA has a potential therapeutic effect against type 2 diabe...

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Detalles Bibliográficos
Autores principales: WATADANI, Risa, KOTOH, Jun, SASAKI, Daiki, SOMEYA, Azusa, MATSUMOTO, Kozo, MAEDA, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2017
Materias:
Laboratory Animal Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627335/
https://www.ncbi.nlm.nih.gov/pubmed/28740028
http://dx.doi.org/10.1292/jvms.17-0348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627335/
https://www.ncbi.nlm.nih.gov/pubmed/28740028
http://dx.doi.org/10.1292/jvms.17-0348

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