Inflammatory Th17 Cells Express Integrin α(v)β(3) for Pathogenic Function

Inerleukin-23 (IL-23) is required for inflammatory Th17 cell function in experimental autoimmune encephalomyelitis (EAE), and IL-23 blockade reduces the number of effector Th17 cells in the CNS. We report that pro-inflammatory Th17 cells express high integrin β(3) that is IL-23 dependent. Integrin β...

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Detalles Bibliográficos
Autores principales: Du, Fang, Garg, Abhishek V., Kosar, Karis, Majumder, Saikat, Kugler, David G., Mir, Gerard Hernandez, Maggio, Maria, Henkel, Matthew, Lacy-Hulbert, Adam, McGeachy, Mandy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627357/
https://www.ncbi.nlm.nih.gov/pubmed/27452457
http://dx.doi.org/10.1016/j.celrep.2016.06.065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627357/
https://www.ncbi.nlm.nih.gov/pubmed/27452457
http://dx.doi.org/10.1016/j.celrep.2016.06.065

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