Oleate ameliorates palmitate-induced reduction of NAMPT activity and NAD levels in primary human hepatocytes and hepatocarcinoma cells

BACKGROUND: Nicotinamide phosphoribosyltransferase (NAMPT) and nicotinamide adenine dinucleotide (NAD) levels are crucial for liver function. The saturated fatty acid palmitate and the unsaturated fatty acid oleate are the main free fatty acids in adipose tissue and human diet. We asked how these fa...

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Detalles Bibliográficos
Autores principales: Penke, Melanie, Schuster, Susanne, Gorski, Theresa, Gebhardt, Rolf, Kiess, Wieland, Garten, Antje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627432/
https://www.ncbi.nlm.nih.gov/pubmed/28974242
http://dx.doi.org/10.1186/s12944-017-0583-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627432/
https://www.ncbi.nlm.nih.gov/pubmed/28974242
http://dx.doi.org/10.1186/s12944-017-0583-6

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