Block-based characterization of protease specificity from substrate sequence profile

BACKGROUND: The mechanism of action of proteases has been widely studied based on substrate specificity. Prior research has been focused on the amino acids at a single amino acid site, but rarely on combinations of amino acids around the cleavage bond. RESULTS: We propose a novel block-based approac...

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Detalles Bibliográficos
Autores principales: Qi, Enfeng, Wang, Dongyu, Gao, Bo, Li, Yang, Li, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627433/
https://www.ncbi.nlm.nih.gov/pubmed/28974219
http://dx.doi.org/10.1186/s12859-017-1851-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627433/
https://www.ncbi.nlm.nih.gov/pubmed/28974219
http://dx.doi.org/10.1186/s12859-017-1851-1

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