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Block-based characterization of protease specificity from substrate sequence profile
BACKGROUND: The mechanism of action of proteases has been widely studied based on substrate specificity. Prior research has been focused on the amino acids at a single amino acid site, but rarely on combinations of amino acids around the cleavage bond. RESULTS: We propose a novel block-based approac...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627433/ https://www.ncbi.nlm.nih.gov/pubmed/28974219 http://dx.doi.org/10.1186/s12859-017-1851-1 |