Molecular features that predict the response to antimetabolite chemotherapies

BACKGROUND: Antimetabolite chemotherapeutic agents that target cellular metabolism are widely used in the clinic and are thought to exert their anti-cancer effects mainly through non-specific cytotoxic effects. However, patients vary dramatically with respect to treatment outcome, and the sources of...

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Detalles Bibliográficos
Autores principales: Mehrmohamadi, Mahya, Jeong, Seong Ho, Locasale, Jason W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627437/
https://www.ncbi.nlm.nih.gov/pubmed/29026541
http://dx.doi.org/10.1186/s40170-017-0170-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627437/
https://www.ncbi.nlm.nih.gov/pubmed/29026541
http://dx.doi.org/10.1186/s40170-017-0170-3

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