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Molecular features that predict the response to antimetabolite chemotherapies
BACKGROUND: Antimetabolite chemotherapeutic agents that target cellular metabolism are widely used in the clinic and are thought to exert their anti-cancer effects mainly through non-specific cytotoxic effects. However, patients vary dramatically with respect to treatment outcome, and the sources of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627437/ https://www.ncbi.nlm.nih.gov/pubmed/29026541 http://dx.doi.org/10.1186/s40170-017-0170-3 |