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Agonists for G-protein-coupled receptor 84 (GPR84) alter cellular morphology and motility but do not induce pro-inflammatory responses in microglia

BACKGROUND: Several G-protein-coupled receptors (GPCRs) have been shown to be important signaling mediators between neurons and glia. In our previous screening for identification of nerve injury-associated GPCRs, G-protein-coupled receptor 84 (GPR84) mRNA showed the highest up-regulation by microgli...

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Detalles Bibliográficos
Autores principales: Wei, Li, Tokizane, Kyohei, Konishi, Hiroyuki, Yu, Hua-Rong, Kiyama, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627487/
https://www.ncbi.nlm.nih.gov/pubmed/28974234
http://dx.doi.org/10.1186/s12974-017-0970-y