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Activation of Casein Kinase II by Gallic Acid Induces BIK–BAX/BAK-Mediated ER Ca(++)-ROS-Dependent Apoptosis of Human Oral Cancer Cells

Induction of the generation of endoplasmic reticulum (ER) calcium (Ca(++))-mediated reactive oxygen species (ROS) by gallic acid (GA) has been implicated in the mitochondrial apoptotic death of human oral cancer (OC) cells, but the molecular mechanism by which GA causes ER Ca(++) release of OC cells...

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Detalles Bibliográficos
Autores principales: Lin, Meng-Liang, Chen, Shih-Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627504/
https://www.ncbi.nlm.nih.gov/pubmed/29033852
http://dx.doi.org/10.3389/fphys.2017.00761