Complement-dependent and -independent aquaporin 4-antibody-mediated cytotoxicity in human astrocytes: Pathogenetic implications in neuromyelitis optica

BACKGROUND: Neuromyelitis optica (NMO) is an inflammatory disease caused by the aquaporin (AQP)-4-antibody. Pathological studies on NMO have revealed extensive astrocytic damage, as evidenced by the loss of AQP4 and glial fibrillary acidic protein (GFAP), specifically in perivascular regions with im...

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Detalles Bibliográficos
Autores principales: Nishiyama, S., Misu, T., Nuriya, M., Takano, R., Takahashi, T., Nakashima, I., Yasui, M., Itoyama, Y., Aoki, M., Fujihara, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627508/
https://www.ncbi.nlm.nih.gov/pubmed/29114578
http://dx.doi.org/10.1016/j.bbrep.2016.05.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627508/
https://www.ncbi.nlm.nih.gov/pubmed/29114578
http://dx.doi.org/10.1016/j.bbrep.2016.05.012

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