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Proinflammatory Effect of High Glucose Concentrations on HMrSV5 Cells via the Autocrine Effect of HMGB1

Background: Peritoneal fibrosis, in which inflammation and apoptosis play crucial pathogenic roles, is a severe complication associated with the treatment of kidney failure with peritoneal dialysis (PD) using a glucose-based dialysate. Mesothelial cells (MCs) take part in the inflammatory processes...

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Detalles Bibliográficos
Autores principales: Chu, Yuening, Wang, Yi, Zheng, Zhihuang, Lin, Yuli, He, Rui, Liu, Jun, Yang, Xuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627536/
https://www.ncbi.nlm.nih.gov/pubmed/29033853
http://dx.doi.org/10.3389/fphys.2017.00762