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The double-edged role of copper in the fate of amyloid beta in the presence of anti-oxidants

The biological fate of amyloid beta (Aβ) species is a fundamental question in Alzheimer’s disease (AD) pathogenesis. The competition between clearance and aggregation of Aβs is critical for the onset of AD. Copper has been widely considered to be an inducer of harmful crosslinking of Aβs, and an imp...

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Detalles Bibliográficos
Autores principales: Yang, Jing, Zhang, Xueli, Zhu, Yiying, Lenczowski, Emily, Tian, Yanli, Yang, Jian, Zhang, Can, Hardt, Markus, Qiao, Chunhua, Tanzi, Rudolph E., Moore, Anna, Ye, Hui, Ran, Chongzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627602/
https://www.ncbi.nlm.nih.gov/pubmed/28989646
http://dx.doi.org/10.1039/c7sc01787a