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The double-edged role of copper in the fate of amyloid beta in the presence of anti-oxidants
The biological fate of amyloid beta (Aβ) species is a fundamental question in Alzheimer’s disease (AD) pathogenesis. The competition between clearance and aggregation of Aβs is critical for the onset of AD. Copper has been widely considered to be an inducer of harmful crosslinking of Aβs, and an imp...
Autores principales: | Yang, Jing, Zhang, Xueli, Zhu, Yiying, Lenczowski, Emily, Tian, Yanli, Yang, Jian, Zhang, Can, Hardt, Markus, Qiao, Chunhua, Tanzi, Rudolph E., Moore, Anna, Ye, Hui, Ran, Chongzhao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627602/ https://www.ncbi.nlm.nih.gov/pubmed/28989646 http://dx.doi.org/10.1039/c7sc01787a |
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