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Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1

PURPOSE: To determine the impact of the loss of syndecan 1 (SDC1) on intraepithelial corneal nerves (ICNs) during homeostasis, aging, and in response to 1.5-mm trephine and debridement injury. METHODS: Whole-mount corneas are used to quantify ICN density and thickness over time after birth and in re...

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Detalles Bibliográficos
Autores principales: Pal-Ghosh, Sonali, Tadvalkar, Gauri, Stepp, Mary Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677/
https://www.ncbi.nlm.nih.gov/pubmed/28973369
http://dx.doi.org/10.1167/iovs.17-21531