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Protective effects on myocardial infarction model: delivery of schisandrin B using matrix metalloproteinase-sensitive peptide-modified, PEGylated lipid nanoparticles

PURPOSE: Schisandrin B (Sch B) is clinically applied for the treatment of hepatitis and ischemic disease. However, its clinical efficacy is limited due to the poor solubility and low bioavailability. This study aimed to develop matrix metalloproteinase (MMP)-sensitive peptide-modified, polyethylene...

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Detalles Bibliográficos
Autores principales: Shao, Mingfeng, Yang, Wenfang, Han, Guangying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627750/
https://www.ncbi.nlm.nih.gov/pubmed/29026305
http://dx.doi.org/10.2147/IJN.S141549