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Delivery of antagomiR204-conjugated gold nanoparticles from PLGA sheets and its implication in promoting osseointegration of titanium implant in type 2 diabetes mellitus

Impaired osseointegration of the implant remains the big hurdle for dental implant therapy in diabetic patients. In this study, the authors first identified that miR204 was strikingly highly expressed in the bone mesenchymal stem cells (BMSCs) of diabetic rats. Forced expression of miR204 repressed...

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Detalles Bibliográficos
Autores principales: Liu, Xiangwei, Tan, Naiwen, Zhou, Yuchao, Wei, Hongbo, Ren, Shuai, Yu, Fan, Chen, Hui, Jia, Chengming, Yang, Guodong, Song, Yingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627761/
https://www.ncbi.nlm.nih.gov/pubmed/29026303
http://dx.doi.org/10.2147/IJN.S124584