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Plumbagin-loaded aptamer-targeted poly d,l-lactic-co-glycolic acid-b-polyethylene glycol nanoparticles for prostate cancer therapy
Plumbagin inhibits the growth, metastasis, and invasion of prostate cancer (PCa). However, its lower bioavailability limits biopharmaceutical properties due to insolubility in water. Prostate-specific membrane antigen (PSMA) aptamer-targeted nanoparticles (NPs) significantly enhanced cytotoxicity in...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627808/ https://www.ncbi.nlm.nih.gov/pubmed/28746182 http://dx.doi.org/10.1097/MD.0000000000007405 |