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PKCζ as a promising therapeutic target for TNFα-induced inflammatory disorders in chronic cutaneous wounds

Protein kinase Cζ (PKCζ) is a member of the atypical protein kinase C family. Its roles in macrophages or skin-resident keratinocytes have not been fully evaluated. In this study, we provide evidence that PKCζ mediates lipopolysaccharide (LPS)-induced tumor necrosis factor α (TNFα) gene expression i...

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Detalles Bibliográficos
Autores principales: Zhang, Jian, Yang, Xuekang, Wang, Hongtao, Zhao, Bin, Wu, Xue, Su, Linlin, Xie, Songtao, Wang, Yunchuan, Li, Jun, Liu, Jiaqi, Liu, Mengdong, Han, Fu, He, Ting, Zhang, Wei, Tao, Ke, Hu, Dahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627866/
https://www.ncbi.nlm.nih.gov/pubmed/28949382
http://dx.doi.org/10.3892/ijmm.2017.3144