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Androgen-independent LNCaP cells are a subline of LNCaP cells with a more aggressive phenotype and androgen suppresses their growth by inducing cell cycle arrest at the G1 phase

Androgen deprivation therapy (ADT, surgical or chemical castration) is the mainstay treatment for metastatic prostate cancer (PCa); however, patients ineluctably relapse despite extremely low androgen levels. This evolution of PCa indicates its lethal progression. In this study, to mimic the traits...

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Detalles Bibliográficos
Autores principales: Yu, Pan, Duan, Xiuzhi, Cheng, Yue, Liu, Chunhua, Chen, Yuhua, Liu, Weiwei, Yin, Binbin, Wang, Xuchu, Tao, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627872/
https://www.ncbi.nlm.nih.gov/pubmed/28901378
http://dx.doi.org/10.3892/ijmm.2017.3125