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MicroRNA-132 induces temozolomide resistance and promotes the formation of cancer stem cell phenotypes by targeting tumor suppressor candidate 3 in glioblastoma

The prognosis of patients suffering from glioblastoma [also referred to as glioblastoma multiforme (GBM)] is dismal despite multimodal therapy. Chemotherapy with temozolomide may suppress tumor growth for a certain period of time (a few months); however, invariable tumor recurrence suggests that gli...

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Detalles Bibliográficos
Autores principales: Cheng, Zhen-Xiu, Yin, Wen-Bo, Wang, Zhong-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627876/
https://www.ncbi.nlm.nih.gov/pubmed/28901390
http://dx.doi.org/10.3892/ijmm.2017.3124