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Protective effects of heme oxygenase-1-transduced bone marrow-derived mesenchymal stem cells on reduced-size liver transplantation: Role of autophagy regulated by the ERK/mTOR signaling pathway

Autophagy is a critical lysosomal pathway that degrades cytoplasmic components to maintain cell homeostasis and provide substrates for energy metabolism. A study revealed that heme oxygenase-1 (HO-1)-transduced bone marrow-derived mesenchymal stem cells (BM-MSCs) could protect 50% reduced-size liver...

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Detalles Bibliográficos
Autores principales: Wang, Raorao, Shen, Zhongyang, Yang, Liu, Yin, Mingli, Zheng, Weiping, Wu, Bin, Liu, Tao, Song, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627878/
https://www.ncbi.nlm.nih.gov/pubmed/28901391
http://dx.doi.org/10.3892/ijmm.2017.3121