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Lipids and ions traverse the membrane by the same physical pathway in the nhTMEM16 scramblase

From bacteria to mammals, different phospholipid species are segregated between the inner and outer leaflets of the plasma membrane by ATP-dependent lipid transporters. Disruption of this asymmetry by ATP-independent phospholipid scrambling is important in cellular signaling, but its mechanism remai...

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Detalles Bibliográficos
Autores principales: Jiang, Tao, Yu, Kuai, Hartzell, H Criss, Tajkhorshid, Emad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628016/
https://www.ncbi.nlm.nih.gov/pubmed/28917060
http://dx.doi.org/10.7554/eLife.28671